The medical drama returned after that jaw-dropping fall finale.

Here's what we know about what's ahead so far.

Can you guess which is the most-hated episode, according to these fans?

The diagnosis mirrors the current story of his on-screen character.

Plus, a cancer scare puts an OG in trouble.

The apologies were a-flowing on Thursday's episode.

It looks like Teddy is moving on with Cass, so should Owen get together with his childhood friend now, too?

The character was first introduced all the way back in Season 7.

The actress also reflected on being part of the show's 450th episode milestone.

'We don't just kill characters off to kill characters off.'